The End Of Dental Fillings?

dental filling

These days, treating large cavities means getting injections and spending a lot of time at the dentist. In the future, fixing a big lesion, might be as simple as placing a sticky sponge or gel into the cavity.

Researchers at King’s College London have discovered that a drug currently in clinical trials to treat neurological disorders, called Tideglusib, was effective in stimulating stem cells in the pulp to heal the tooth naturally by creating dentine, which is the part of the tooth that covers and protects the pulp.

The researchers simply applied the drug to the cavities via a collagen sponge. They found that when the sponges degraded, dentine was formed in its pace, leading to natural complete repair.

This type of approach could eliminate the need for drilling leaving the tooth healthier and more intact after treatment.

To find out more about this, read the King’s College London article in Scientific Reports

Promotion of natural tooth repair by small molecule GSK3 antagonists

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